2069 – Armstrong Outpost at Shackleton Crater becomes the first human settlement on Luna. It is formally founded on July 24, the 100th anniversary of the first lunar landing.
2103 – Lowell City in Eos Chasma becomes the first human settlement on Mars.
2137 – Eldfell-Ashland Energy Corporation demonstrates helium-3 fuel extraction from the atmosphere of Saturn.
2142 – Construction of Gagarin Station (Jump Zero) begins beyond the orbit of Pluto.
2148 – Prospectors discover the Prothean ruins at Promethei Planum on Mars.
2149 – Translation of Prothean data leads humans to the Charon mass relay. Systems Alliance founded to coordinate exploration and colonization of extra-solar worlds.
2151 – A shipping accident at Singapore International Spaceport exposes downwind communities to containers of dust-form element zero. Alliance begins construction of Arcturus Station.
2152 – Roughly 30% of the children born in Singapore after element zero exposure suffer from cancerous growths. Systems Alliance begins settlement of Earth’s first extra-solar colony world, the planet Demeter.
2154 – Commander Shepard born.
2155 – Systems Alliance occupies completed portions of Arcturus Station as a headquarters.
2156 – Some children of Singapore exhibit minor telekinetic abilities.
2157 – Turians encounter human explorers; First Contact War. Occupation and liberation of the human colony of Shanxi.
2158 – Humans learn potential of biotics. An international effort to track element zero exposures begins. Roughly 10% of exposed children show some level of biotic ability.
2160 – Systems Alliance Parliament formed.
2165 – Humans establish embassy on Citadel.
2170 – Batarian slavers attack the Alliance colony of Mindoir.
2176 – Skyllian Blitz – Pirates and slavers attacked Elysium, the human capital in the Skyllian Verge.
2177 – Thresher maws devour the Alliance colony of Akuze.
2178 – In retaliation for the Skyllian Blitz, an Alliance fleet wipes out an army of slavers on the moon of Torfan.
2183 – Geth led by rogue Spectre Saren Arterius attack the Citadel, ensuing in a battle that cost thousands of lives. A few weeks later, the SSV Normandy is ambushed and destroyed. Commander Shepard is presumed dead.
2185 – An alien race known as the Collectors abducts thousands of human colonists in the Terminus Systems. Commander Shepard leads a team beyond the Omega 4 relay to attack the Collectors where they live, stopping the abductions.
2186 – Current date.